| # | Tým | Z | V | R | P | Skóre | B |
|---|---|---|---|---|---|---|---|
| 1 | TJ Tatran Bohunice | 12 | 8 | 3 | 1 | 26:10 | 27 |
| 2 | FC Kuřim | 12 | 8 | 2 | 2 | 33:18 | 26 |
| 3 | FC Boskovice | 12 | 7 | 2 | 3 | 19:12 | 23 |
| 4 | FC Ivančice | 11 | 6 | 3 | 3 | 27:19 | 21 |
| 5 | SK Líšeň "B" | 12 | 6 | 1 | 4 | 21:16 | 19 |
| 6 | TJ Tatran Rousínov | 12 | 5 | 4 | 3 | 27:24 | 19 |
| 7 | SK Olympia Ráječko | 12 | 5 | 3 | 4 | 29:26 | 18 |
| 8 | FC Sparta Brno | 12 | 6 | 0 | 6 | 26:24 | 18 |
| 9 | FK SK Bosonohy | 12 | 5 | 2 | 5 | 18:20 | 17 |
| 10 | FC Baník Ratíškovice | 12 | 5 | 0 | 7 | 18:22 | 15 |
| 11 | Dosta Bystrc-Kníničky | 12 | 3 | 5 | 4 | 16:16 | 14 |
| 12 | SK Krumvíř | 12 | 4 | 1 | 7 | 15:25 | 13 |
| 13 | FC Svratka Brno | 12 | 3 | 2 | 7 | 16:24 | 11 |
| 14 | FC Moravský Krumlov | 12 | 2 | 3 | 7 | 12:24 | 9 |
| 15 | FK Mutěnice | 11 | 2 | 2 | 7 | 11:22 | 8 |
| 16 | MS Brno | 10 | 2 | 1 | 7 | 11:23 | 7 |
| # | Datum | Čas | Zápas | Výsledek | |
| 2 | So | 7.8.2021 | 17:30 | Mutěnice - Bohunice | 0:3 |
| 3 | So | 14.8.2021 | 10:15 | Bohunice - Ratíškovice | 4:0 |
| 4 | So | 21.8.2021 | 10:00 | Boskovice - Bohunice | 2:1 |
| 5 | So | 28.8.2021 | 10:15 | Bohunice - Bystrc | 2:2 |
| 6 | So | 4.9.2021 | 16:30 | Krumvíř - Bohuncie | 0:1 |
| 7 | So | 11.9.2021 | 10:15 | Bohunice - Kuřim | 3:2 |
| 8 | Ne | 19.92021 | 16:00 | Ráječko - Bohunice | 1:1 |
| 9 | So | 25.9.2021 | 10:15 | Bohunice - MS Brno | 4:0 |
| 10 | So | 2.10.2021 | 15:30 | Ivančice - Bohunice | 2:3 |
| 11 | So | 9.10.2021 | 10:15 | Bohunice - Svratka Brno | 0:0 |
| 12 | So | 16.10.2021 | 15:00 | Sparta Brno - Bohunice | 1:3 |
| 13 | So | 23.10.2021 | 10:15 | Bohunice - Mor. Krumlov | 1:0 |
| 14 | Čt | 28.10.2021 | 10:15 | Bohunice - Rousínov | |
| 1 | Ne | 31.10.2021 | 10:15 | Bohunice - Líšeň "B" | |
| 15 | So | 6.11.2021 | 14:00 | Bosonohy - Bohunice | |
